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Biohacking, nootropics, and the notion of optimizing one's human performance are on a rapid rise. Nootrobox founders Geoffrey Woo and Michael Brandt are some of the foremost thinkers in this space, and they are here to have intellectual conversations that will make you THINK every Monday.

 

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Apr 15, 2019

Wait...hasn't ketones been shown to reduce inflammation in prior studies?

When a new study researched the effects ketones have on inflammation, the results were opposite to what everyone expected...including the researchers themselves.

The paper was published in the Journal of Molecular Nutrition and Food Research, and the research group that carried out the work were led by Dr Jonathan Little at the University of British Columbia.

Rather than inhibiting the inflammatory response through BHB’s (a ketone body) actions on the NLRP3 inflammasome, the researchers found that activity of several immune markers was higher when people had consumed ketones.

It can be easy to jump to conclusions and state that "Exogenous Ketones = Increased Inflammation"...as the title of the paper acutely suggests.

Dr. Brianna Stubbs tackles this study and provides further, necessary nuance on how the experiment was conducted, why the results may actually be more positive than negative, and why this development warrants future research.

Referenced Studies:
1. https://onlinelibrary.wiley.com/doi/full/10.1002/mnfr.201801171
2. https://www.ncbi.nlm.nih.gov/pubmed/30239561

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